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post #1 of 10 (permalink) Old 03-21-2018, 08:20 AM Thread Starter
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DNA Tests

Has anyone here used DNA tests to see if doggie is sensitive to anesthesia?

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post #2 of 10 (permalink) Old 03-21-2018, 09:20 AM
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I don't believe there is any DNA test that would tell you that.


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post #3 of 10 (permalink) Old 03-21-2018, 09:57 AM Thread Starter
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I saw this in a review for Embark on Amazon. Only one reviewer mentioned it so I wasn't sure if the claim was legit.

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post #4 of 10 (permalink) Old 03-21-2018, 10:10 AM
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breed differences but not a genetic test http://healthypets.mercola.com/sites...lications.aspx
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post #5 of 10 (permalink) Old 03-21-2018, 12:42 PM
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That makes more sense.


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post #6 of 10 (permalink) Old 03-21-2018, 01:53 PM
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I asked our IAABC member who is a dog genetics expert for her thoughts and she said ...
"There is one known genetic variant, for MDR-1, that will tell you if a dog might not handle anesthesia well. There is a test for that. There are definitely other genetic factors that will affect a dog's risk of not handling anesthesia well, but we don't yet know what they are.


The MDR-1 variant is common in herding breeds and it's a great idea to test for it in them. In others, it's quite rare if ever seen at all, so not so useful.

Just because a dog is MDR-1 negative does not guarantee they will do well under anesthesia.

I hope that helps! "

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post #7 of 10 (permalink) Old 03-21-2018, 04:00 PM Thread Starter
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Quote:
Originally Posted by davetgabby View Post
I asked our IAABC member who is a dog genetics expert for her thoughts and she said ...
"There is one known genetic variant, for MDR-1, that will tell you if a dog might not handle anesthesia well. There is a test for that. There are definitely other genetic factors that will affect a dog's risk of not handling anesthesia well, but we don't yet know what they are.


The MDR-1 variant is common in herding breeds and it's a great idea to test for it in them. In others, it's quite rare if ever seen at all, so not so useful.

Just because a dog is MDR-1 negative does not guarantee they will do well under anesthesia.

I hope that helps! "

Jessica

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The Dog Zombie | Jessica Perry Hekman, DVM, PhD
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The MDR-1 variant is what the one review on Amazon said the test indicated. Sounds like of no use in toy breeds to check for it. I will let my daughter know, she might want to check her collies.

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post #8 of 10 (permalink) Old 03-21-2018, 04:16 PM
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Yes, it would seem to me that this MIGHT be hepful in mixed breeds. Like the Collie problems with certain heartworm meds.

Quote:
Originally Posted by davetgabby View Post
I asked our IAABC member who is a dog genetics expert for her thoughts and she said ...
"There is one known genetic variant, for MDR-1, that will tell you if a dog might not handle anesthesia well. There is a test for that. There are definitely other genetic factors that will affect a dog's risk of not handling anesthesia well, but we don't yet know what they are.


The MDR-1 variant is common in herding breeds and it's a great idea to test for it in them. In others, it's quite rare if ever seen at all, so not so useful.

Just because a dog is MDR-1 negative does not guarantee they will do well under anesthesia.

I hope that helps! "

Jessica

Jessica P. Hekman, DVM, PhD
The Dog Zombie | Jessica Perry Hekman, DVM, PhD
Dogs! Brains! Science!


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plus Starborn's Picture Perfect & Nauti Herd Compact Flash RN, CGC, NTD, SN-C, RL1)






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post #9 of 10 (permalink) Old 03-22-2018, 04:58 AM
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I don’t think it is a “DNA” test but I know my vet does blood tests to determine whether a cat or dog will have a negative reaction to the standard anaesthetic before they have surgery.
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post #10 of 10 (permalink) Old 03-22-2018, 08:57 AM
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Originally Posted by Paddington View Post
I don’t think it is a “DNA” test but I know my vet does blood tests to determine whether a cat or dog will have a negative reaction to the standard anaesthetic before they have surgery.
Yes, those SHOULD always be done before any procedure that requires anesthesia. They are to look at the overall health of the dog and that they are in condition to withstand the anesthesia and the procedure.


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