Hi Shirley, I'm a dental hygienist for people. I looked over their website. One ingredient is papain which I believe is used as a meat tenderizer. One would assume that"s safe to ingest(?) if it's OK to use on meat. The other ingredients look healthy. However, I just can't imagine how it actually will inhibit or clean off plaque. The plain old toothbrush is the proven winner at that task.