Merle gene - Havanese Forum : Havanese Forums
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post #1 of 17 (permalink) Old 07-31-2012, 12:31 PM Thread Starter
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Merle gene

Maybe

Last edited by amrileb7; 10-20-2012 at 06:53 PM. Reason: Misspelling
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post #2 of 17 (permalink) Old 07-31-2012, 07:30 PM
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What is that gene for those of us that are not up on genetics?

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post #3 of 17 (permalink) Old 08-01-2012, 04:34 AM
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Thanks for posting, very interesting and definitely not old news! Is there a picture of that merle Havanese?
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post #4 of 17 (permalink) Old 08-01-2012, 08:27 AM
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Eyes

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Originally Posted by amrileb7 View Post
You are very welcome.what was new to me was a Havanese being born with that color,well pattern hehe.No I don't have any pictures,all I know is that the Merle puppies were born without eyes a very common defect in double merles.the thing is that the parents didn't show the Merle pattern.
No eyes!

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post #5 of 17 (permalink) Old 08-01-2012, 08:56 AM
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How very sad. Just another reason that people need to research their breeders before buying!

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post #6 of 17 (permalink) Old 08-01-2012, 01:36 PM
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Originally Posted by amrileb7 View Post
You are very welcome.what was new to me was a Havanese being born with that color,well pattern hehe.No I don't have any pictures,all I know is that the Merle puppies were born without eyes a very common defect in double merles.the thing is that the parents didn't show the Merle pattern.
That's the scary part to me... Considering all the over-lays of genes that go into producing our "rainbow" of Havanese colors, it would be SO easy for a Merle not to be recognized as such. Just think how much our sables fade... many are close to white as adults. Or what if you had a Merle who also had the silver gene... they could grey out enough that they might not be recognized. Definitely a scary thought for breeders.

This looks like something breeders might want to do genetic testing to discover if they have it in their lines. (and is yet another important reason for BAER testing of any puppy a buyer is considering!!!)


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post #7 of 17 (permalink) Old 08-01-2012, 02:49 PM
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Before anyone gets too upset the reason many of our Havs are born dark and lighten is due to the A, Agouti gene with a co dominant, this is found on chromosome 24. This is found in several different breds also inc. the Lowchen.

There is also the G, graying gene it can take up to four years to complete, it is found in some shih tzus and is why the Yorkie''s coats turn blue.

M, merle is very complex and of course is now considered a fragile gene.

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post #8 of 17 (permalink) Old 08-01-2012, 02:53 PM
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Originally Posted by The Laughing Magpie View Post
Before anyone gets too upset the reason many of our Havs are born dark and lighten is due to the A, Agouti gene with a co dominant, this is found on chromosome 24. This is found in several different breds also inc. the Lowchen.

There is also the G, graying gene it can take up to four years to complete, it is found in some shih tzus and is why the Yorkie''s coats turn blue.

M, merle is very complex and of course is now considered a fragile gene.
Oh, I know. And I am assuming it is quite rare at this point. The worrisome part is that it could be covered up by other coat genes, and cause someone to unsuspectingly breed two dogs with the gene.

I don't think this is a huge problem for the pet owner anyway, as long as the pups are BAER tested, as they should be in any case. It's something that breeders will have to be on the watch for, however. The breeders would be the ones dealing with the heart ache of lethal white (or severely defective) puppies.


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post #9 of 17 (permalink) Old 08-01-2012, 03:17 PM
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Genmark has a test for M, this is why it is important to go to a good breeder and this is an example of why purebreds are a good bet as their lines have been followed. If a Breeder thought that their Havanese showed a merle they could have the parents tested as this is autosomal, means it could be father or mother, if they found the gene they would retire the parents or better yet if there were a question they would test the parents first. I too think this is rare in the Havanese the scary part of course is back yard breeders and large scale breeding operations.

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post #10 of 17 (permalink) Old 08-01-2012, 04:34 PM
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This is why so many people were against adding the color Blue to the Standard last time.
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